macOS: 10.4, 10.3, 10.2
Hamachi: 2.1.0.821
This started with just one Hamachi installation but is now happening with multiple Hamach installations. When I try to connect to a remote peer the network is good (green dot) but the peer is not available (clear dot). On the peer system one or more of the Hamachi processes (LogMein Hamachi, LogmeIn Hamachi Menubar, and/or hamachid) show a CPU % of 99% or higher. Using the Acivity Monitor to force quit these processes will fix the issue, or a system reboot.
This seems to happen eventually to any system running Hamachi longer than a few weeks, which is problematic.